Do nonspecific symptoms have you
questioning the diagnosis?
It could be HLH
Hemophagocytic lymphohistiocytosis (HLH) is a rare and potentially fatal syndrome characterized by a rapidly progressive state of maladaptive hyperinflammation. It presents with a range of nonspecific signs and symptoms of multisystem distress that can overlap with other conditions, making the diagnostic process difficult.1 Find out how to identify this dangerous immune dysregulation in your patients before it’s too late.
MULTISYSTEM DISTRESS1
MULTISYSTEM DISTRESS1
Persistent high fever
Central nervous system involvement
Rash
Hyperferritinemia
Hepatosplenomegaly
Hypertriglyceridemia
Cytopenias
Hemophagocytic lymphohistiocytosis (HLH) is a rare and potentially fatal syndrome characterized by a rapidly progressive state of maladaptive hyperinflammation. It presents with a range of nonspecific signs and symptoms of multisystem distress that can overlap with other conditions, making the diagnostic process difficult.1 Find out how to identify this dangerous immune dysregulation in your patients before it’s too late.
Reference: 1. Jordan MB, Allen CE, Weitzman S, Filipovich AH, McClain KL. How I treat hemophagocytic lymphohistiocytosis. Blood. 2011;118(15):4041-4052. doi:10.1182/blood-2011-03-278127